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Clinical Efficacy

The efficacy of GelX® Oral Spray has been evaluated 
and proven in a number of clinical studies.

Niculita et al, 2020 5

The Efficacy of Polyvinylpyrrolidone- Zn Gluconate and Taurine (GelX®) in the prevention of Oral Mucositis in Haematological Patients.


A study of 145 patients made up of 99 adults (68.27%) and 46 children (31.72%). All 145 patients received GelX® Oral Spray for preventing OM.

  • The prevention of OM was achieved in 54 patients (37.24%) [22 adults, 32 children] where patients developed no OM at all.
  • In the remaining patients who developed symptoms of OM, 93.4% had a complete remission of symptoms.

Colita et al, 20156

The Efficacy of Polyvinylpyrrolidone-Zinc Gluconate and Taurine Gel (GelX®) 
in Prophylaxis and Treatment of Oral Mucositis in Children Treated with Chemotherapy.


GelX® Oral Spray was administered 
prophylactically or as a curative in this study.

  • There was no difference in the median value 
of tolerability of GelX® between the 2 groups.
  • In the prophylaxis arm, there was a significant reduction of OM 
severity with better results in quality of life, pain control and oral intake.

Dragomir et al, 20157

The Efficacy of Polyvinylpyrrolidone-Zinc Gluconate and Taurine Gel (GelX®) 
in Prevention and Treatment of Chemotherapy-Induced Oral Mucositis in Children with Cancer.


GelX® Oral Spray in Prevention and Treatment of Chemotherapy-induced Oral Mucositis in Children with Cancer.

  • Pain was reduced in 80% of patients after the treatment with GelX® Oral Spray.
  • Swallowing difficulties were reduced in 74% of patients
  • There were no delays in treatment caused by severity of OM
  • It was concluded that GelX® Oral Spray prevents severe mucositis and promotes healing

Zannier et al, 201916

Effects of Three Products in the Prevention and Treatment of Chemotherapy and Radiation Therapy-induced Oral Mucositis.


Sixty adult patients were randomised into 3 arms to receive either GelX® Oral Spray (Group 1), Episil Oral Solution (Group 2) or Gelclair Oral Gel (Group 3).

  • The GelX® Oral Spray group demonstrated an overall better efficacy and grade of safety compared to the other two groups.