GelX® is a mucoprotectant brand available in a 100ml oral solution spray, indicated for the prevention and treatment of oral mucositis and suitable for use in all ages and all
ethnic cultures. 1
Provides a bio-adhesive barrier for durable protection
Blocks exposed nerve endings and coats oral lesions to soothe and relieve pain 1,4
Aids patients in coping with oral mucositis and completing long-term treatment goals. 5
How does it work? 12,13
Mode of Action
Biomechanical Benefits
- Bio adhesive barrier for durable protection
- Blocks exposed nerve endings and coats oral lesions to soothe and relieve pain
- Protects ulcerated tissue from further injury and bacterial colonisation
Anti-inflammation
- Adheres to mucosal surface and delivers a bioactive zinc-taurine complex
- Releases bioactive zinc-taurine complex into epithelial cells
- The combined anti-inflammatory properties of zinc and taurine have demonstrated a synergistic biological effect in vitro by regulating COX-2 mediated prostaglandins and inflammatory cytokines
Ingredients
Polyvinylpyrrolidone (PVP)
- High molecular weight polymer
- Coating and encapsulation of tissues
- Provides a water-permeable film
Zinc Gluconate and Taurine
- Forms a bio-active zinc-taurine complex under physiological conditions
- Provides excellent bacteriostatic qualities without cyto-toxicity seen in other preservative systems
- Effective in addressing mineral deficiency and inflammatory processes associated with oral pain and discomfort
- Found to exert anti-microbial, anti-inflammatory, free radical scavenging, and analgesic effects
- Delays onset of oral mucositis by inhibiting inflammatory cycle
Clinical Evidence
- The use of GelX® in the prevention and soothing of cancer-therapy-induced oral mucositis has been clinically proven in children and adults suffering from a variety of malignancies. 5,6,7
- The preventive use of GelX® when starting radiotherapy has been shown to reduce the severity of mucositis. 5
- The preventive use of GelX® has been shown to reduce the severity of oral mucositis (WHO scale) during chemotherapy and improve eating and swallowing in children. 6,7
- GelX® reduces the need to interrupt chemotherapy or radiotherapy treatment due to oral mucositis. 5
- GelX® reduces pain and swallowing difficulties caused by chemotherapy-induced oral mucositis in children with cancer. 6
